GLP-1 & metabolic
5-Amino-1MQ
2.5–5 mg daily
Reconstitution
| Vial | 2 mL water | 4 mL water |
|---|---|---|
| 50 mg | 25 mg/mL | 12.5 mg/mL |
A 4 mL fill on the 50 mg vial gives 12.5 mg/mL, which keeps the small daily draws easy to measure. It can sting a little going in, so inject slowly.
- Use bacteriostatic water as the diluent.
- Add the water slowly, letting it run down the inside wall of the vial rather than onto the powder.
- Swirl gently to mix, then leave it to dissolve. Do not shake.
- Give it a few minutes. The finished solution should be clear and colourless.
Protocol
Route: Subcutaneous
Standard protocol (subcutaneous)
- 2.5 mg to 5 mg per day, once daily
- Start at the low end (2.5 mg) for the first week to assess tolerance, then move toward 5 mg
- At a 4 mL fill (12.5 mg/mL), 5 mg is a 0.4 mL draw (40 units)
Dosing detail
- Injectable dosing is commonly 2.5 mg to 5 mg per day. (Oral capsules use far higher amounts because of low oral absorption; this is the injectable.)
- Once daily is typical. Some split into two smaller doses.
- An NNMT inhibitor that raises NAD+ and supports fat oxidation. It works best with diet, not instead of it.
- Mild sting on injection is common; go slow.
Duration
- Run in 4 to 8 week blocks, ideally during a calorie-deficit phase, since it works best paired with diet.
Notes
- A small molecule studied for metabolism and fat cells (NNMT inhibition).
- Generally well tolerated.
- Inject subcutaneously and rotate sites.
Storage and handling
- Keep the powdered (lyophilized) vial in a cool, dark place. Refrigerate it for longer-term storage before mixing.
- Once reconstituted and refrigerated at 2–8 °C away from light, use the vial within 90 days.
- Do not freeze a reconstituted vial, and keep it away from heat and sunlight.
- If the solution turns cloudy, develops floating particles, or shows any other sign of degradation, stop using that vial.