Growth hormone · Muscle growth and tissue repair enhancement
IGF-1 LR3
20–40 mcg daily
Synthetic IGF-1 analog engineered for longer half-life and reduced binding to IGF-binding proteins, making it far more potent than natural IGF-1. Used in research on cell growth and differentiation, but widely misused in bodybuilding for muscle building.
Important: IGF-1 peptides are insulin-like and can drop your blood sugar. Eat a meal with protein and carbs shortly after injecting, watch for low blood sugar signs, and do not inject within 2 hours of bedtime (overnight hypoglycaemia risk).
Reconstitution
| Vial | 1 mL water | 2 mL water |
|---|---|---|
| 1 mg | 1 mg/mL | 0.5 mg/mL |
As with IGF-1 DES, bac water is the common practical diluent for a vial used within its window. A low-pH diluent is sometimes preferred for longer storage.
- Use bacteriostatic water as the diluent.
- Add the water slowly, letting it run down the inside wall of the vial rather than onto the powder.
- Swirl gently to mix, then leave it to dissolve. Do not shake.
- Give it a few minutes. The finished solution should be clear and colourless.
Protocol
Route: Subcutaneous or intramuscular
Standard protocol (subcutaneous or intramuscular)
- Beginners: 0.02 mg to 0.04 mg (20 to 40 mcg) per day, once daily, ideally post-workout
- Start at the low end and assess tolerance for the first 1 to 2 weeks
- Do not exceed 0.05 mg/day (50 mcg) without real experience
Dosing detail
- Beginner dose is 0.02 mg to 0.04 mg (20 to 40 mcg) once daily. Intermediate 0.05 to 0.08 mg (50 to 80 mcg).
- Long-acting, so once daily is enough. Post-workout or morning is the usual timing.
- Eat after dosing and avoid late-night injections to prevent overnight low blood sugar.
- Cycle 4 to 6 weeks on, equal time off, to keep receptors responsive.
Duration
- Run 4 to 6 weeks, then an equal time off: it is long-acting (20 to 30 hour half-life) and the receptors downregulate with continuous use.
Notes
- A long-acting IGF-1 variant, systemic rather than purely local.
- Watch for low blood sugar signs.
- Inject subcutaneously and rotate sites.
Storage and handling
- Keep the powdered (lyophilized) vial in a cool, dark place. Refrigerate it for longer-term storage before mixing.
- Once reconstituted and refrigerated at 2–8 °C away from light, use the vial within 90 days.
- Do not freeze a reconstituted vial, and keep it away from heat and sunlight.
- If the solution turns cloudy, develops floating particles, or shows any other sign of degradation, stop using that vial.