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Library · Muscle, bone & joint · Joint cartilage protection and regeneration support

Cartalax (Ala-Glu-Asp)

AED peptide, Ala-Glu-Asp tripeptide, Cartalax bioregulator

Synthetic tripeptide (Ala-Glu-Asp) from the early 2000s, studied for cartilage protection and joint health. Preclinical work suggests it may regulate cartilage-degrading enzymes and support proteoglycan/collagen production; remains an unapproved research peptide with limited human data.

Research score 65/100. Reference only, not a dose.

  • Joint Support
  • Anti-inflammatory
  • Recovery Enhancement
  • Pain Relief
US status
Research Chemical
Approval
Research Chemical Only
Evidence
Synthetic tripeptide bioregulator targeting cartilage and connective tissue. Used for joint health and osteoarthritis.
Research score
65 / 100
Indication
Research Only - No Medical Indication
Origin
Russia
Source category
Muscles & Joints
Status group
Research chemical

Mechanism

Interacts with chondrocyte receptors to boost proteoglycan and type II collagen synthesis, inhibits cartilage-degrading MMPs while raising TIMPs, reduces IL-1β/TNF-α inflammation, and supports chondrocyte survival via PI3K/Akt signaling.

Safety file

Generally reported well tolerated where used, with possible mild allergic reaction or injection-site irritation; long-term human safety data is scarce.

  • Injection site reactions
  • Joint stiffness
  • Temporary joint discomfort
  • Mild inflammation