Library · Muscle, bone & joint · Cartilage and joint tissue regeneration support
Chonluten (Glu-Asp-Arg)
EDR peptide, Glu-Asp-Arg, Chonluten bioregulator
Synthetic tripeptide (Glu-Asp-Arg) from 1990s research into joint and cartilage support. Animal studies suggest possible joint-health benefits through anti-inflammatory and repair-promoting activity; remains an unapproved research peptide with limited human study.
Research score 70/100. Reference only, not a dose.
- Joint Support
- Healing
- Anti-inflammatory
- Recovery Enhancement
- US status
- Research Chemical
- Approval
- Research Chemical Only
- Evidence
- Tripeptide bioregulator with affinity for lung and gastrointestinal tissues. Studied for anti-inflammatory and gene regulation effects.
- Research score
- 70 / 100
- Indication
- Research Only - No Medical Indication
- Origin
- Russia
- Source category
- Muscles & Joints
- Status group
- Research chemical
Mechanism
Acts on chondrocyte receptors to boost proteoglycan and type II collagen synthesis, suppresses IL-1β/TNF-α via reduced NF-κB signaling, supports chondrocyte survival through PI3K/Akt, and lowers cartilage-degrading MMP expression.
Safety file
Reported to have minimal side effects in bioregulator research, but lacks rigorous human safety data; long-term effects are unknown.
- Injection site reactions
- Mild joint discomfort
- Temporary inflammation