Library · Reproductive · Labor induction and social bonding enhancement
Oxytocin
Pitocin, Syntocinon, OXT, OT
A hypothalamic neuropeptide hormone used clinically to induce labor and control postpartum bleeding. It is also studied intensively, often via nasal spray, for its roles in bonding and trust and for conditions like autism, PTSD, and anxiety.
Research score 90/100. Reference only, not a dose.
- Hormone Regulation
- Mood Enhancement
- Stress Relief
- Anxiety Reduction
- Fertility Enhancement
- US status
- Prescription Only
- Approval
- FDA + EMA Approved
- Evidence
- FDA approved for labor induction/PPH. Investigated for FTD, PTSD, pain (intranasal).
- Research score
- 90 / 100
- Indication
- Labor Induction
- Origin
- UK
- Source category
- Reproductive System
- Status group
- Approved / prescription
Mechanism
Binds oxytocin receptors, activating phospholipase C-β and calcium signaling to drive uterine and myoepithelial contraction; in the brain it modulates the amygdala and reward circuits, affecting trust and bonding, and sensitizes the uterus to prostaglandins during labor.
Safety file
Safe at doses used in obstetrics; high doses risk water intoxication or uterine rupture; nasal use is generally mild, with occasional dizziness or headache.
- Uterine hyperstimulation
- Nausea
- Vomiting
- Arrhythmia
- Hypertension
- Water intoxication