Library · Muscle, bone & joint · Muscle growth and repair enhancement
PEG-MGF
PEGylated MGF, Polyethylene Glycol-Mechano Growth Factor, PEG-IGF-1Ec
A PEGylated form of MGF (IGF-1Ec), the IGF-1 splice variant induced by muscle strain, used in research to extend the compound's activity for studying muscle repair and hypertrophy.
Research score 35/100. Reference only, not a dose.
- Muscle Growth
- Recovery Enhancement
- Joint Support
- Healing
- Angiogenesis
- US status
- Research Chemical
- Approval
- Research Chemical Only
- Evidence
- No specific human clinical trials found (2020-2025). Preclinical tissue repair studies.
- Research score
- 35 / 100
- Indication
- Research Only - No Medical Indication
- Origin
- UK
- Source category
- Muscles & Joints
- Status group
- Research chemical
Mechanism
Works through the IGF-1 receptor with a focus on satellite-cell activation; PEGylation extends its half-life, sustaining PI3K/Akt/mTOR-driven protein synthesis, satellite-cell fusion, and VEGF-mediated local blood-vessel growth.
Safety file
Human safety data are absent; theoretical cancer risk mirrors that of IGF-1.
- Injection site reactions
- Water retention
- Joint pain
- Potential impact on blood sugar levels