Library · Digestive & liver · Tissue healing and gastrointestinal repair
BPC-157
Bepecin, PL 14736, PL-10, Pentadecapeptide BPC 157
Synthetic peptide based on a protective gastric-juice protein, studied in animals for angiogenesis, cellular repair, and cytoprotective/anti-inflammatory effects on tendons, ligaments, gut, and brain. Not FDA-approved, classified as an unapproved drug, and banned by WADA; human evidence is very limited.
Research score 60/100. Reference only, not a dose.
- Healing
- Anti-inflammatory
- Gut Health
- Joint Support
- Wound Healing
- Recovery Enhancement
- US status
- Unapproved New Drug (FDA Category 2 bulk drug substance). Prohibited by WADA.
- Approval
- Not FDA Approved for human or animal use.
- Evidence
- Limited Human Studies
- Research score
- 60 / 100
- Indication
- Research Only - No Medical Indication
- Origin
- Croatia
- Source category
- Digestive System
- Status group
- Research chemical
Mechanism
Raises VEGF-driven blood vessel formation and growth-hormone receptor expression, boosts collagen formation, and activates the FAK-paxillin pathway for cell migration; also promotes nitric oxide release and mucosal defense in the gut.
Safety file
Appears safe in animals with no reported toxicity, but human safety data from controlled trials is lacking; theoretical concern about supporting tumor growth via VEGFR2 activation.
- Injection site reactions (pain, swelling, infection, allergic reactions)