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Library · Reproductive · Male reproductive system and testosterone support

Testagen (Lys-Glu-Asp-Gly)

Lys-Glu-Asp-Gly, KEDG peptide, Testagen peptide

A synthetic tetrapeptide (Lys-Glu-Asp-Gly) 'bioregulator' studied for male reproductive health, aimed at normalizing testosterone, sperm quality, and sexual function by influencing gene expression in the testes.

Research score 40/100. Reference only, not a dose.

  • Hormone Regulation
  • Fertility Enhancement
  • Libido Enhancement
  • Recovery Enhancement
US status
Research Chemical
Approval
Research Chemical Only
Evidence
Russian studies. No FDA approval.
Research score
40 / 100
Indication
Research Only - No Medical Indication
Origin
Russia
Source category
Reproductive System
Status group
Research chemical

Mechanism

Enhances signaling along the hypothalamic-pituitary-gonadal axis, raising LH and FSH release to boost testosterone production in Leydig cells and support sperm production in Sertoli cells, partly via increased StAR protein expression and antioxidant protection of reproductive tissue.

Safety file

Generally described as safe within its bioregulator class; mild side effects reported.

  • Injection site reactions
  • Hormone level fluctuations
  • Mood changes