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Library · Skin & hair · Skin regeneration and photoprotection

SLU-PP-332

SLU-PP-332, PP-332, SLU-332

A novel synthetic agonist targeting estrogen-related receptors alpha, beta, and gamma, often described as an 'exercise mimetic' for its potential to raise metabolic endurance and preserve muscle function without exercise. It remains in preclinical development.

Research score 45/100. Reference only, not a dose.

  • Skin Health
  • Collagen Production
  • Wound Healing
  • Photoprotection
  • Melanin Production
US status
Research Chemical
Approval
Research Chemical Only
Evidence
Preclinical only. No human trials found (2020-2025).
Research score
45 / 100
Indication
Cosmetic/Anti-aging
Origin
USA
Source category
Skin & Dermatology
Status group
Research chemical

Mechanism

The published mechanism text for this entry describes a different compound, so it is left out here.

Safety file

Animal studies indicate good safety, without liver or kidney toxicity; a theoretical risk of cardiac hypertrophy via ERR-gamma activation exists.

  • Mild skin irritation
  • Temporary redness
  • Contact dermatitis in sensitive individuals