Library · Heart, blood & kidney · Cardiovascular system support and blood vessel health
Vesugen (Lys-Glu-Asp)
KED peptide, Lys-Glu-Asp tripeptide, Vessel bioregulator peptide
A synthetic tripeptide (Lys-Glu-Asp) bioregulator studied for vascular health, particularly in older adults, aimed at improving blood flow, reducing atherosclerosis, and supporting blood-vessel wall repair.
Research score 45/100. Reference only, not a dose.
- Cardiovascular Health
- Blood Pressure Regulation
- Anti-aging
- Angiogenesis
- US status
- Research Chemical
- Approval
- Research Chemical Only
- Evidence
- Used in Russia. Limited Western clinical data (2020-2025).
- Research score
- 45 / 100
- Indication
- Research Only - No Medical Indication
- Origin
- Russia
- Source category
- Heart & Cardiovascular
- Status group
- Research chemical
Mechanism
Acts on vascular endothelial cells via NO/cGMP signaling, boosting nitric oxide synthase activity to aid vasodilation and microcirculation, engaging calcium and PI3K/Akt signaling for endothelial survival and vessel integrity, and modulating VEGF to support controlled vessel repair.
Safety file
Good short-term safety profile; no significant side effects reported.
- Injection site reactions
- Mild blood pressure fluctuations
- Temporary dizziness