Library · Skin & hair · Skin regeneration and wound healing
AHK-Cu (Copper Peptide)
Copper Tripeptide-1, AHK-Cu, L-Alanyl-L-Histidyl-L-Lysine Copper Complex
Synthetic copper-binding tripeptide (Ala-His-Lys) modeled on GHK-Cu, built for better stability and skin penetration. Studied for collagen stimulation, wound healing, and skin remodeling; mainly used in cosmetic products, not clinically approved.
Research score 80/100. Reference only, not a dose.
- Skin Health
- Collagen Production
- Wound Healing
- Anti-aging
- Hair Growth
- Anti-inflammatory
- US status
- Research Chemical
- Approval
- Cosmetic Use Only
- Evidence
- Promotes hair follicle elongation and proliferation of dermal papilla cells. Used as a gentler alternative to Minoxidil.
- Research score
- 80 / 100
- Indication
- Cosmetic/Anti-aging
- Origin
- USA
- Source category
- Skin & Dermatology
- Status group
- Research chemical
Mechanism
Delivers copper into cells, activating lysyl oxidase and prolyl hydroxylase to build collagen and elastin, while balancing MMP and TIMP activity for matrix remodeling. Also spurs VEGF-driven vessel growth and fibroblast/keratinocyte migration.
Safety file
Well tolerated with low toxicity; occasional mild local irritation or redness. Absorption profile resembles GHK-Cu.
- Skin irritation
- Redness
- Temporary sensitivity
- Contact dermatitis in sensitive individuals