Library · Skin & hair · Skin regeneration and wound healing
GHK Basic (Tripeptide-1)
GHK, Tripeptide-1, Kollaren, Prezatide, Liver growth factor
Copper-free version of the tripeptide GHK (Tripeptide-1), a signaling molecule known for boosting collagen production, wound healing, and skin anti-aging effects. Common ingredient in high-end skincare.
Research score 70/100. Reference only, not a dose.
- Skin Health
- Collagen Production
- Wound Healing
- Anti-inflammatory
- Antioxidant
- US status
- Research Chemical
- Approval
- Cosmetic Use Only
- Evidence
- Cosmetic clinical studies showing efficacy for skin aging.
- Research score
- 70 / 100
- Indication
- Cosmetic/Anti-aging
- Origin
- USA
- Source category
- Skin & Dermatology
- Status group
- Research chemical
Mechanism
Modulates matrix metalloproteinases and binds cell-surface receptors and copper to drive collagen and proteoglycan synthesis, fibroblast growth and migration, and release of VEGF, FGF, and NGF; also engages TGF-β/SMAD signaling and antioxidant defenses.
Safety file
Safe for topical use; irritation is rare.
- Well-tolerated with minimal side effects