Library · Immune · Antioxidant and immune system support
Glutathione
GSH, Reduced glutathione, γ-L-Glutamyl-L-cysteinyl-glycine
Naturally occurring tripeptide (glutamine, cysteine, glycine) first isolated in 1888, known as the body’s main antioxidant, supporting detoxification, immune function, and oxidative stress defense. Supplemental forms are used medically and in wellness settings; IV delivery gives the highest bioavailability since oral absorption is limited.
Research score 85/100. Reference only, not a dose.
- Antioxidant
- Immune Boosting
- Detoxification
- Liver Protection
- Anti-inflammatory
- US status
- OTC
- Approval
- Multiple Approved Indications
- Evidence
- Extensive Human Studies
- Research score
- 85 / 100
- Indication
- Multiple Approved Indications
- Origin
- USA
- Source category
- Immune System
- Status group
- Approved / prescription
Mechanism
Cycles between reduced and oxidized forms, with its cysteine thiol group neutralizing free radicals directly and serving as a cofactor for detox enzymes; supports T-cell function, dampens NF-κB-driven inflammation, and binds toxins/heavy metals for elimination.
Safety file
Excellent.
- Generally well-tolerated with minimal side effects at standard doses