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Library · Brain & nerves · Cognitive enhancement and anxiety reduction

N-Acetyl Selank Amidate

N-Ac-Selank-NH2, Acetyl-Selank amide, N-Acetyl-TKPRPGP-amide

A modified, acetylated and amidated version of the tuftsin-derived peptide Selank, designed for greater stability, potency, and brain penetration. Studied as a research compound for cognition, mood, and immune balance; not FDA-approved.

Research score 60/100. Reference only, not a dose.

  • Cognitive Enhancement
  • Anxiety Reduction
  • Neuroprotective
  • Memory Enhancement
  • Stress Relief
US status
Research Chemical
Approval
Not FDA Approved for human use. Sold for laboratory research use only.
Evidence
Animal + In Vitro Studies
Research score
60 / 100
Indication
Research Only - No Medical Indication
Origin
Russia
Source category
Brain & Nervous System
Status group
Research chemical

Mechanism

Modulates GABA receptor activity and raises BDNF expression, stabilizes enkephalins for sustained calming and cognitive effects, and adjusts IL-6 and other inflammatory markers while affecting serotonin and norepinephrine turnover.

Safety file

Generally well tolerated, similar to standard Selank; occasional nasal irritation, headache, irritability, or dizziness reported; long-term data limited.

  • Mild headache
  • Nasal irritation
  • Temporary drowsiness
  • Altered mood
  • Irritability
  • Dizziness