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Library · Immune · Liver protection and immune system regulation

Livagen (Lys-Glu-Asp-Ala)

KEDA peptide, Immunomodulating tetrapeptide, Liver bioregulator peptide

Short synthetic peptide bioregulator (Lys-Glu-Asp-Ala) studied for modulating chromatin structure and gene expression, potentially reversing age-related DNA changes. Acts on immune, liver, and gut tissue, mainly researched in anti-aging and immune-normalization contexts.

Research score 50/100. Reference only, not a dose.

  • Liver Protection
  • Immune Boosting
  • Anti-inflammatory
  • Detoxification
US status
Research Chemical
Approval
Research Chemical Only
Evidence
Used in Russia. Limited specific 'Livagen' clinical trials in Western databases (2020-2025).
Research score
50 / 100
Indication
Research Only - No Medical Indication
Origin
Russia
Source category
Immune System
Status group
Research chemical

Mechanism

Interacts with nuclear factors in liver cells to shift gene expression toward anti-inflammatory cytokines over pro-inflammatory ones via JAK/STAT signaling, while supporting hepatocyte survival and regeneration through NF-κB-linked protective pathways and boosted detox enzyme expression.

Safety file

Considered safe as a bioregulator, with only theoretical mild side effects.

  • Injection site reactions
  • Mild fatigue
  • Temporary immune system fluctuations