Library · Skin & hair · Research compound for interfering with melanin production.
Melanostatin DM
MIF-1, Melanocyte-Stimulating Hormone Release-Inhibiting Factor 1, PLG-NH2, L-Prolyl-L-leucylglycinamide, Melanostatin
Synthetic peptide (also called MIF-1) derived from melanostatin, studied for its ability to inhibit alpha-MSH and reduce melanin production for lighter skin tone. Not FDA-approved; used as a research compound.
Research score 30/100. Reference only, not a dose.
- Melanin Inhibition
- Skin Lightening
- US status
- Research Chemical
- Approval
- Not FDA Approved
- Evidence
- Animal + In Vitro Studies
- Research score
- 30 / 100
- Indication
- Research Only - Melanin Inhibition
- Origin
- USA
- Source category
- Skin & Dermatology
- Status group
- Research chemical
Mechanism
Inhibits alpha-MSH, the hormone that drives melanin production, reducing tyrosinase enzyme activity and thereby melanin synthesis.
Safety file
Generally considered safe topically; animal research shows possible skin irritation, redness, rash, or temporary burning. Sold for research use only, not intended for human use.
- Headache
- Mild nausea
- Temporary dizziness
- Changes in mood