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Library · Immune · Immune system regulation and cellular protection

Ovagen (Glu-Asp-Ala-Gly)

EDAG peptide, Glu-Asp-Ala-Gly, Epitalon-like peptide

A Russian-developed synthetic tetrapeptide (Glu-Asp-Ala-Gly) intended as a 'bioregulator' to support ovarian function. Studied within Russia but lacking recent research in major international databases; not FDA or EMA approved, and sold online as a supplement or research chemical.

Research score 70/100. Reference only, not a dose.

  • Immune Boosting
  • Anti-inflammatory
  • DNA Repair
  • Antioxidant
US status
Research Chemical
Approval
Not Approved by FDA/EMA
Evidence
Synthetic tetrapeptide liver bioregulator. Used for liver support and metabolic regulation.
Research score
70 / 100
Indication
Research Only - No Medical Indication
Origin
Russia
Source category
Immune System
Status group
Research chemical

Mechanism

An immunomodulatory peptide acting through JAK/STAT signaling in T-lymphocytes and macrophages, raising anti-inflammatory cytokines and antioxidant defenses such as glutathione, while also affecting NF-κB signaling.

Safety file

Oral forms are generally described as well tolerated; unregulated injectable versions carry infection and contamination risk; robust human safety data are lacking.

  • Injection site reactions
  • Mild immune system fluctuations
  • Temporary fatigue