Library · Skin & hair · Skin inflammation reduction and anti-aging
Rigin (Palmitoyl Tetrapeptide-7)
Palmitoyl Tetrapeptide-7, Pal-GQPR, Palmitoyl-Gly-Gln-Pro-Arg
Also called Palmitoyl Tetrapeptide-7, this early-2000s cosmetic peptide targets skin inflammation and aging by lowering interleukin-6 output. Lab studies show reduced inflammatory markers and improved collagen synthesis, though it remains a cosmetic rather than therapeutic ingredient.
Research score 45/100. Reference only, not a dose.
- Skin Health
- Anti-inflammatory
- Collagen Production
- Inflammation Resolution
- US status
- Research Chemical
- Approval
- Cosmetic Use Only
- Evidence
- Limited Human Studies
- Research score
- 45 / 100
- Indication
- Cosmetic/Anti-aging
- Origin
- France
- Source category
- Skin & Dermatology
- Status group
- Research chemical
Mechanism
Its palmitoyl group aids skin penetration while the peptide portion curbs UV- and stimulus-triggered IL-6 overproduction, lowering matrix-metalloproteinase activity and helping maintain balanced collagen turnover and glycosaminoglycan synthesis.
Safety file
Good tolerability profile.
- Well-tolerated with minimal side effects