Library · Immune · Immune system regulation and enhancement
Thymogen
EW dipeptide, Glu-Trp, Immunofan, Timogen, Thymagen
A Russian-developed synthetic dipeptide (Glu-Trp), also called Thymagen, used there as an immune-modulating 'bioregulator,' including for viral infections and dental disease. Recent large-scale international clinical data are lacking; not FDA or EMA approved and sold online as a research chemical.
Research score 40/100. Reference only, not a dose.
- Immune Boosting
- Anti-inflammatory
- Anti-viral
- Anti-bacterial
- Inflammation Resolution
- US status
- Research Chemical
- Approval
- Not Approved by FDA/EMA
- Evidence
- Limited to Russian studies; no recent, large-scale clinical trials found in major international databases.
- Research score
- 40 / 100
- Indication
- Immune Deficiency (in Russia)
- Origin
- Russia
- Source category
- Immune System
- Status group
- Research chemical
Mechanism
Promotes immature T-cell maturation in the thymus, raising CD3+/CD4+ marker expression and adjusting the CD4+/CD8+ ratio; believed to bind DNA and nuclear proteins to activate JAK/STAT signaling, increasing IL-2 and IFN-γ output, boosting NK-cell and macrophage activity, and reducing inflammation via NF-κB modulation.
Safety file
Reported as well tolerated with low toxicity in Russian use, but not confirmed by large modern Western clinical trials.
- Local injection site reactions
- Mild allergic reactions
- Temporary fatigue
- Appetite changes
- Mood changes